| Keyboard Shortcut | Menu Shortcut | Menu Location |
| Esc (see Note) | Alt+S, L | Selection -> Clear Selection |
The Clear Selection command deselects all selected entities or regions.
Note: For some drawing commands, the Esc key will remove the last point that was set instead of clearing the selection. Also, in Image Mode, a Selection tool must be currently active for Esc to clear the selection (however, you may run the command from the menu regardless of whether a selection tool is active or not).